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Visualization of the Effect of Assay Size on the Error Profile of Tumor Mutational Burden Measurement
Tumor mutational burden (TMB) refers to the number of somatic mutations in a tumor per megabase and is a biomarker for response to immune checkpoint inhibitor therapy. Immune checkpoint inhibitors are currently approved for tumors with TMB greater than or equal to 10 mutations/megabase. Many laborat...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8949329/ https://www.ncbi.nlm.nih.gov/pubmed/35327986 http://dx.doi.org/10.3390/genes13030432 |