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Visualization of the Effect of Assay Size on the Error Profile of Tumor Mutational Burden Measurement

Tumor mutational burden (TMB) refers to the number of somatic mutations in a tumor per megabase and is a biomarker for response to immune checkpoint inhibitor therapy. Immune checkpoint inhibitors are currently approved for tumors with TMB greater than or equal to 10 mutations/megabase. Many laborat...

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Detalles Bibliográficos
Autor principal:	Bailey, Nathanael G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8949329/ https://www.ncbi.nlm.nih.gov/pubmed/35327986 http://dx.doi.org/10.3390/genes13030432

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