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The Power of Single-Cell RNA Sequencing in eQTL Discovery

Genome-wide association studies have successfully mapped thousands of loci associated with complex traits. During the last decade, functional genomics approaches combining genotype information with bulk RNA-sequencing data have identified genes regulated by GWAS loci through expression quantitative...

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Detalles Bibliográficos
Autores principales: Maria, Maleeha, Pouyanfar, Negar, Örd, Tiit, Kaikkonen, Minna U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8949403/
https://www.ncbi.nlm.nih.gov/pubmed/35328055
http://dx.doi.org/10.3390/genes13030502