Mineralizing Gelatin Microparticles as Cell Carrier and Drug Delivery System for siRNA for Bone Tissue Engineering

The local release of complexed siRNA from biomaterials opens precisely targeted therapeutic options. In this study, complexed siRNA was loaded to gelatin microparticles cross-linked (cGM) with an anhydride-containing oligomer (oPNMA). We aggregated these siRNA-loaded cGM with human mesenchymal stem...

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Detalles Bibliográficos
Autores principales: Hinkelmann, Sandra, Springwald, Alexandra H., Schulze, Sabine, Hempel, Ute, Mitrach, Franziska, Wölk, Christian, Hacker, Michael C., Schulz-Siegmund, Michaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8949427/
https://www.ncbi.nlm.nih.gov/pubmed/35335924
http://dx.doi.org/10.3390/pharmaceutics14030548

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8949427/
https://www.ncbi.nlm.nih.gov/pubmed/35335924
http://dx.doi.org/10.3390/pharmaceutics14030548

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