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Mineralizing Gelatin Microparticles as Cell Carrier and Drug Delivery System for siRNA for Bone Tissue Engineering
The local release of complexed siRNA from biomaterials opens precisely targeted therapeutic options. In this study, complexed siRNA was loaded to gelatin microparticles cross-linked (cGM) with an anhydride-containing oligomer (oPNMA). We aggregated these siRNA-loaded cGM with human mesenchymal stem...
Autores principales: | Hinkelmann, Sandra, Springwald, Alexandra H., Schulze, Sabine, Hempel, Ute, Mitrach, Franziska, Wölk, Christian, Hacker, Michael C., Schulz-Siegmund, Michaela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8949427/ https://www.ncbi.nlm.nih.gov/pubmed/35335924 http://dx.doi.org/10.3390/pharmaceutics14030548 |
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