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pH-Responsive Nanoparticles for Delivery of Paclitaxel to the Injury Site for Inhibiting Vascular Restenosis

A high incidence of restenosis has been reported at the site of inflammation following angioplasty and stent implantation. The anti-proliferative drug paclitaxel (PTX) could help to reduce inflammation and restenosis; however, it has poor water solubility and serious adverse side effects at high dos...

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Detalles Bibliográficos
Autores principales: Zhu, Huiru, Kong, Li, Zhu, Xu, Ran, Tingting, Ji, Xiaojuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8949492/
https://www.ncbi.nlm.nih.gov/pubmed/35335910
http://dx.doi.org/10.3390/pharmaceutics14030535