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Radiosynthesis and Preclinical Evaluation of Bispecific PSMA/FAP Heterodimers for Tumor Imaging

Due to tumor heterogeneity and complex tumor–stromal interactions in multicellular systems, the efficiency of monospecific tracers for tumor diagnosis and therapy is currently limited. In light of the evidence of prostate-specific membrane antigen (PSMA) overexpression in tumor cells and fibroblast...

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Detalles Bibliográficos
Autores principales: Hu, Kongzhen, Li, Li, Huang, Yong, Ye, Shimin, Zhong, Jiawei, Yan, Qingsong, Zhong, Yuhua, Fu, Lilan, Feng, Pengju, Li, Hongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8949503/
https://www.ncbi.nlm.nih.gov/pubmed/35337180
http://dx.doi.org/10.3390/ph15030383