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Aurasperone A Inhibits SARS CoV-2 In Vitro: An Integrated In Vitro and In Silico Study

Several natural products recovered from a marine-derived Aspergillus niger were tested for their inhibitory activity against SARS CoV-2 in vitro. Aurasperone A (3) was found to inhibit SARS CoV-2 efficiently (IC(50) = 12.25 µM) with comparable activity with the positive control remdesivir (IC(50) =...

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Detalles Bibliográficos
Autores principales: ElNaggar, Mai H., Abdelwahab, Ghada M., Kutkat, Omnia, GabAllah, Mohamed, Ali, Mohamed A., El-Metwally, Mohamed E. A., Sayed, Ahmed M., Abdelmohsen, Usama Ramadan, Khalil, Ashraf T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8949533/
https://www.ncbi.nlm.nih.gov/pubmed/35323478
http://dx.doi.org/10.3390/md20030179