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Dually Active Polycation/miRNA Nanoparticles for the Treatment of Fibrosis in Alcohol-Associated Liver Disease

Alcohol-associated liver disease (AALD) is a major cause of liver disorders worldwide. Current treatment options are limited, especially for AALD-associated fibrosis. Promising approaches include RNA interference for miR-155 overexpression in Kupffer cells (KCs), as well as the use of CXCR4 antagoni...

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Detalles Bibliográficos
Autores principales: Zhang, Chuhan, Hang, Yu, Tang, Weimin, Sil, Diptesh, Jensen-Smith, Heather C., Bennett, Robert G., McVicker, Benita L., Oupický, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8949580/
https://www.ncbi.nlm.nih.gov/pubmed/35336043
http://dx.doi.org/10.3390/pharmaceutics14030669