Cancer-Associated Fibroblasts Regulate Kinase Activity in Mesothelioma Cell Lines via Paracrine Signaling and Thereby Dictate Cell Faith and Behavior

Background: Malignant pleural mesothelioma (MPM) has an infaust prognosis due to resistance to systemic treatment with platin-analoga. MPM cells modulate the immune response to their benefit. They release proinflammatory cytokines, such as TGF-ß, awakening resting fibrocytes that switch their phenot...

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Detalles Bibliográficos
Autores principales: Mathilakathu, Alexander, Wessolly, Michael, Mairinger, Elena, Uebner, Hendrik, Kreidt, Daniel, Brcic, Luka, Steinborn, Julia, Greimelmaier, Kristina, Wohlschlaeger, Jeremias, Schmid, Kurt Werner, Mairinger, Fabian D., Borchert, Sabrina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8949651/
https://www.ncbi.nlm.nih.gov/pubmed/35328699
http://dx.doi.org/10.3390/ijms23063278

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8949651/
https://www.ncbi.nlm.nih.gov/pubmed/35328699
http://dx.doi.org/10.3390/ijms23063278

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