Cargando…
Cancer-Associated Fibroblasts Regulate Kinase Activity in Mesothelioma Cell Lines via Paracrine Signaling and Thereby Dictate Cell Faith and Behavior
Background: Malignant pleural mesothelioma (MPM) has an infaust prognosis due to resistance to systemic treatment with platin-analoga. MPM cells modulate the immune response to their benefit. They release proinflammatory cytokines, such as TGF-ß, awakening resting fibrocytes that switch their phenot...
Autores principales: | Mathilakathu, Alexander, Wessolly, Michael, Mairinger, Elena, Uebner, Hendrik, Kreidt, Daniel, Brcic, Luka, Steinborn, Julia, Greimelmaier, Kristina, Wohlschlaeger, Jeremias, Schmid, Kurt Werner, Mairinger, Fabian D., Borchert, Sabrina |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8949651/ https://www.ncbi.nlm.nih.gov/pubmed/35328699 http://dx.doi.org/10.3390/ijms23063278 |
Ejemplares similares
-
Digital Gene Expression Analysis of Epithelioid and Sarcomatoid Mesothelioma Reveals Differences in Immunogenicity
por: Brcic, Luka, et al.
Publicado: (2021) -
Cancer-Associated Fibroblasts Influence Survival in Pleural Mesothelioma: Digital Gene Expression Analysis and Supervised Machine Learning Model
por: Borchert, Sabrina, et al.
Publicado: (2023) -
Induction of metallothionein expression by supplementation of zinc induces resistance against platinum-based treatment in malignant pleural mesothelioma
por: Wyrich, Martine, et al.
Publicado: (2023) -
One Third of Malignant Pleural Mesothelioma Shows High Immunohistochemical Expression of MSLN or CXCR4 Which Indicates Potent Candidates for Endo-Radiotherapy
por: Hager, Thomas, et al.
Publicado: (2023) -
Mitogen signal-associated pathways, energy metabolism regulation, and mediation of tumor immunogenicity play essential roles in the cellular response of malignant pleural mesotheliomas to platinum-based treatment: a retrospective study
por: Mathilakathu, Alexander, et al.
Publicado: (2021)