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Spatially Controlled Activation of Toll-like Receptor 9 with DNA-Based Nanomaterials

[Image: see text] First evidence of geometrical patterns and defined distances of biomolecules as fundamental parameters to regulate receptor binding and cell signaling have emerged recently. Here, we demonstrate the importance of controlled nanospacing of immunostimulatory agents for the activation...

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Detalles Bibliográficos
Autores principales: Comberlato, Alice, Koga, Marianna M., Nüssing, Simone, Parish, Ian A., Bastings, Maartje M. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8949768/
https://www.ncbi.nlm.nih.gov/pubmed/35266392
http://dx.doi.org/10.1021/acs.nanolett.2c00275