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Formation of Ciprofloxacin–Isonicotinic Acid Cocrystal Using Mechanochemical Synthesis Routes—An Investigation into Critical Process Parameters

The mechanochemical synthesis of cocrystals has been introduced as a promising approach of formulating poorly water-soluble active pharmaceutical ingredients (APIs). In this study, hot-melt extrusion (HME) as a continuous process and grinding and ball milling as batch processes were employed to expl...

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Detalles Bibliográficos
Autores principales: Karimi-Jafari, Maryam, Ziaee, Ahmad, O’Reilly, Emmet, Croker, Denise, Walker, Gavin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8949855/
https://www.ncbi.nlm.nih.gov/pubmed/35336009
http://dx.doi.org/10.3390/pharmaceutics14030634