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Cytolytic Properties and Genome Analysis of Rigvir(®) Oncolytic Virotherapy Virus and Other Echovirus 7 Isolates

Rigvir(®) is a cell-adapted, oncolytic virotherapy enterovirus, which derives from an echovirus 7 (E7) isolate. While it is claimed that Rigvir(®) causes cytolytic infection in several cancer cell lines, there is little molecular evidence for its oncolytic and oncotropic potential. Previously, we ge...

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Detalles Bibliográficos
Autores principales: Hietanen, Eero, Koivu, Marika K. A., Susi, Petri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8949920/
https://www.ncbi.nlm.nih.gov/pubmed/35336934
http://dx.doi.org/10.3390/v14030525