Stabilizing Effect of Soluplus on Erlotinib Metastable Crystal Form in Microparticles and Amorphous Solid Dispersions

Microparticles (MPs) and amorphous solid dispersions (SDs) are effective methods to improve the dissolution of insoluble drugs. However, stability is a concern for these two high-energy systems, resulting from high surface area and amorphous polymorph, respectively. As an amphiphilic polymer, Solupl...

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Detalles Bibliográficos
Autores principales: Jia, Shuyu, Ning, Shangqi, Leng, Yuting, Jing, Qiufang, Xu, Zhongyu, Ren, Fuzheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8949943/
https://www.ncbi.nlm.nih.gov/pubmed/35335571
http://dx.doi.org/10.3390/polym14061241

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8949943/
https://www.ncbi.nlm.nih.gov/pubmed/35335571
http://dx.doi.org/10.3390/polym14061241

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