Effects of a Fully Humanized Type II Anti-CD20 Monoclonal Antibody on Peripheral and CNS B Cells in a Transgenic Mouse Model of Multiple Sclerosis

Successful therapy with anti-CD20 monoclonal antibodies (mAbs) has reinforced the key role of B cells in the immunopathology of multiple sclerosis (MS). This study aimed to determine the effects of a novel class of anti-CD20 mAbs on vascular and extravascular central nervous system (CNS)-infiltratin...

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Detalles Bibliográficos
Autores principales: Tacke, Sabine, Chunder, Rittika, Schropp, Verena, Urich, Eduard, Kuerten, Stefanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8949956/
https://www.ncbi.nlm.nih.gov/pubmed/35328594
http://dx.doi.org/10.3390/ijms23063172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8949956/
https://www.ncbi.nlm.nih.gov/pubmed/35328594
http://dx.doi.org/10.3390/ijms23063172

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