The Rationale for the Dual-Targeting Therapy for RSK2 and AKT in Multiple Myeloma

Multiple myeloma (MM) is characterized by remarkable cytogenetic/molecular heterogeneity among patients and intraclonal diversity even in a single patient. We previously demonstrated that PDPK1, the master kinase of series of AGC kinases, is universally active in MM, and plays pivotal roles in cell...

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Detalles Bibliográficos
Autores principales: Isa, Reiko, Horinaka, Mano, Tsukamoto, Taku, Mizuhara, Kentaro, Fujibayashi, Yuto, Taminishi-Katsuragawa, Yoko, Okamoto, Haruya, Yasuda, Shusuke, Kawaji-Kanayama, Yuka, Matsumura-Kimoto, Yayoi, Mizutani, Shinsuke, Shimura, Yuji, Taniwaki, Masafumi, Sakai, Toshiyuki, Kuroda, Junya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8949999/
https://www.ncbi.nlm.nih.gov/pubmed/35328342
http://dx.doi.org/10.3390/ijms23062919

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8949999/
https://www.ncbi.nlm.nih.gov/pubmed/35328342
http://dx.doi.org/10.3390/ijms23062919

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