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Development of Nanocrystal Compressed Minitablets for Chronotherapeutic Drug Delivery

The present work aimed to develop a chronotherapeutic system of valsartan (VS) using nanocrystal formulation to improve dissolution. VS nanocrystals (VS-NC) were fabricated using modified anti-solvent precipitation by employing a Box–Behnken design to optimize various process variables. Based on the...

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Detalles Bibliográficos
Autores principales: Sreeharsha, Nagaraja, Naveen, Nimbagal Raghavendra, Anitha, Posina, Goudanavar, Prakash S., Ramkanth, Sundarapandian, Fattepur, Santosh, Telsang, Mallikarjun, Habeebuddin, Mohammed, Anwer, Md. Khalid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8950040/
https://www.ncbi.nlm.nih.gov/pubmed/35337109
http://dx.doi.org/10.3390/ph15030311