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Exploring Pharmacological Functions of Alternatively Spliced Variants of the Mu Opioid Receptor Gene, Oprm1, via Gene-Targeted Animal Models

The mu opioid receptor has a distinct place in the opioid receptor family, since it mediates the actions of most opioids used clinically (e.g., morphine and fentanyl), as well as drugs of abuse (e.g., heroin). The single-copy mu opioid receptor gene, OPRM1, goes through extensive alternative pre-mRN...

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Detalles Bibliográficos
Autores principales: Kang, Wenjian, Liu, Shan, Xu, Jin, Abrimian, Anna, Malik, Ayma F., Chien, Raymond, Adaralegbe, Adejuyigbe, Amponsah, Akwasi, Cartegni, Luca, Pintar, John, Pan, Ying-Xian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8950057/
https://www.ncbi.nlm.nih.gov/pubmed/35328429
http://dx.doi.org/10.3390/ijms23063010