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Polymorphic and Higher-Order G-Quadruplexes as Possible Transcription Regulators: Novel Perspectives for Future Anticancer Therapeutic Applications

In the past two decades, significant efforts have been put into designing small molecules to target selected genomic sites where DNA conformational rearrangements control gene expression. G-rich sequences at oncogene promoters are considered good points of intervention since, under specific environm...

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Detalles Bibliográficos
Autores principales: Rigo, Riccardo, Groaz, Elisabetta, Sissi, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8950063/
https://www.ncbi.nlm.nih.gov/pubmed/35337170
http://dx.doi.org/10.3390/ph15030373