A White Plaque, Associated with Genomic Deletion, Derived from M13KE-Based Peptide Library Is Enriched in a Target-Unrelated Manner during Phage Display Biopanning Due to Propagation Advantage

The nonspecific enrichment of target-unrelated peptides during biopanning remains a major drawback for phage display technology. The commercial Ph.D.(TM)-7 phage display library is used extensively for peptide discovery. This library is based on the M13KE vector, which carries the lacZα sequence, le...

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Detalles Bibliográficos
Autores principales: Kamstrup Sell, Danna, Sloth, Ane Beth, Bakhshinejad, Babak, Kjaer, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8950111/
https://www.ncbi.nlm.nih.gov/pubmed/35328728
http://dx.doi.org/10.3390/ijms23063308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8950111/
https://www.ncbi.nlm.nih.gov/pubmed/35328728
http://dx.doi.org/10.3390/ijms23063308

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