Modelling Protein Plasticity: The Example of Frataxin and Its Variants

Frataxin (FXN) is a protein involved in storage and delivery of iron in the mitochondria. Single-point mutations in the FXN gene lead to reduced production of functional frataxin, with the consequent dyshomeostasis of iron. FXN variants are at the basis of neurological impairment (the Friedreich’s a...

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Detalles Bibliográficos
Autores principales: Botticelli, Simone, La Penna, Giovanni, Nobili, Germano, Rossi, Giancarlo, Stellato, Francesco, Morante, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8950120/
https://www.ncbi.nlm.nih.gov/pubmed/35335316
http://dx.doi.org/10.3390/molecules27061955

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8950120/
https://www.ncbi.nlm.nih.gov/pubmed/35335316
http://dx.doi.org/10.3390/molecules27061955

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