The Influenza Virus RNA-Polymerase and the Host RNA-Polymerase II: RPB4 Is Targeted by a PB2 Domain That Is Involved in Viral Transcription

Influenza virus transcription is catalyzed by the viral RNA-polymerase (FluPol) through a cap-snatching activity. The snatching of the cap of cellular mRNA by FluPol is preceded by its binding to the flexible C-terminal domain (CTD) of the RPB1 subunit of RNA-polymerase II (Pol II). To better unders...

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Detalles Bibliográficos
Autores principales: Morel, Jessica, Sedano, Laura, Lejal, Nathalie, Da Costa, Bruno, Batsché, Eric, Muchardt, Christian, Delmas, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8950122/
https://www.ncbi.nlm.nih.gov/pubmed/35336925
http://dx.doi.org/10.3390/v14030518

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8950122/
https://www.ncbi.nlm.nih.gov/pubmed/35336925
http://dx.doi.org/10.3390/v14030518

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