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Antibacterial Activity of Isobavachalcone (IBC) Is Associated with Membrane Disruption

Isobavachalcone (IBC) is a natural prenylated chalcone with a broad spectrum of pharmacological properties. In this work, we newly synthesized and investigated the antibacterial activity of IBC against Gram-positive, Gram-negative and mycobacterial species. IBC was active against Gram-positive bacte...

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Detalles Bibliográficos
Autores principales: de Assis, Leticia Ribeiro, Theodoro, Reinaldo dos Santos, Costa, Maria Beatriz Silva, Nascentes, Julyanna Andrade Silva, da Rocha, Miguel Divino, Bessa, Meliza Arantes de Souza, Menezes, Ralciane de Paula, Dilarri, Guilherme, Hypolito, Giovane Böerner, dos Santos, Vanessa Rodrigues, Duque, Cristiane, Ferreira, Henrique, Martins, Carlos Henrique Gomes, Regasini, Luis Octavio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8950343/
https://www.ncbi.nlm.nih.gov/pubmed/35323743
http://dx.doi.org/10.3390/membranes12030269