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Caveolin-1-Derived Peptide Reduces ER Stress and Enhances Gelatinolytic Activity in IPF Fibroblasts

Idiopathic pulmonary fibrosis (IPF) is a fatal disease characterized by an excess deposition of extracellular matrix in the pulmonary interstitium. Caveolin-1 scaffolding domain peptide (CSP) has been found to mitigate pulmonary fibrosis in several animal models. However, its pathophysiological role...

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Detalles Bibliográficos
Autores principales: Komatsu, Satoshi, Fan, Liang, Idell, Steven, Shetty, Sreerama, Ikebe, Mitsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8950460/
https://www.ncbi.nlm.nih.gov/pubmed/35328736
http://dx.doi.org/10.3390/ijms23063316