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Caveolin-1-Derived Peptide Reduces ER Stress and Enhances Gelatinolytic Activity in IPF Fibroblasts
Idiopathic pulmonary fibrosis (IPF) is a fatal disease characterized by an excess deposition of extracellular matrix in the pulmonary interstitium. Caveolin-1 scaffolding domain peptide (CSP) has been found to mitigate pulmonary fibrosis in several animal models. However, its pathophysiological role...
Autores principales: | Komatsu, Satoshi, Fan, Liang, Idell, Steven, Shetty, Sreerama, Ikebe, Mitsuo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8950460/ https://www.ncbi.nlm.nih.gov/pubmed/35328736 http://dx.doi.org/10.3390/ijms23063316 |
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