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Alleviation of Surgery-Induced Osteitis in Sinonasal Cavity by Dexamethasone-Loaded Poly(lactic-co-glycolic acid) (PLGA) Microparticles with Strong Calcium-Binding Affinity

For the treatment of sinus surgery-induced osteitis in chronic rhinosinusitis (CRS), oral or intranasal administration of corticoids is generally used, although it has critical limitations and unavoidable side effects. To overcome these limitations, we designed dexamethasone (Dex)-loaded poly(lactic...

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Detalles Bibliográficos
Autores principales: Hong, Seung-No, Kim, Minjae, Park, Jin-A, Kang, Minji, Cha, Hyunkyung, Park, Sohyun, Kim, Joon Kon, Pac, Jinyoung, Seo, Yuju, Kim, Sungwhan, Kim, Minju, Kim, Dae Woo, Lee, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8950508/
https://www.ncbi.nlm.nih.gov/pubmed/35335922
http://dx.doi.org/10.3390/pharmaceutics14030546