Clinical Pharmacokinetic Assessment of Kratom (Mitragyna speciosa), a Botanical Product with Opioid-like Effects, in Healthy Adult Participants

Increasing use of the botanical kratom to self-manage opioid withdrawal and pain has led to increased kratom-linked overdose deaths. Despite these serious safety concerns, rigorous fundamental pharmacokinetic knowledge of kratom in humans remains lacking. We assessed the pharmacokinetics of a single...

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Detalles Bibliográficos
Autores principales: Tanna, Rakshit S., Nguyen, James T., Hadi, Deena L., Manwill, Preston K., Flores-Bocanegra, Laura, Layton, Matthew E., White, John R., Cech, Nadja B., Oberlies, Nicholas H., Rettie, Allan E., Thummel, Kenneth E., Paine, Mary F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8950611/
https://www.ncbi.nlm.nih.gov/pubmed/35335999
http://dx.doi.org/10.3390/pharmaceutics14030620

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8950611/
https://www.ncbi.nlm.nih.gov/pubmed/35335999
http://dx.doi.org/10.3390/pharmaceutics14030620

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