Cargando…
Clinical Pharmacokinetic Assessment of Kratom (Mitragyna speciosa), a Botanical Product with Opioid-like Effects, in Healthy Adult Participants
Increasing use of the botanical kratom to self-manage opioid withdrawal and pain has led to increased kratom-linked overdose deaths. Despite these serious safety concerns, rigorous fundamental pharmacokinetic knowledge of kratom in humans remains lacking. We assessed the pharmacokinetics of a single...
Autores principales: | Tanna, Rakshit S., Nguyen, James T., Hadi, Deena L., Manwill, Preston K., Flores-Bocanegra, Laura, Layton, Matthew E., White, John R., Cech, Nadja B., Oberlies, Nicholas H., Rettie, Allan E., Thummel, Kenneth E., Paine, Mary F. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8950611/ https://www.ncbi.nlm.nih.gov/pubmed/35335999 http://dx.doi.org/10.3390/pharmaceutics14030620 |
Ejemplares similares
-
Kratom (
Mitragyna speciosa
) Validation: Quantitative Analysis of Indole and Oxindole Alkaloids Reveals Chemotypes of Plants and Products
por: Manwill, Preston K., et al.
Publicado: (2022) -
Chemical composition and biological effects of kratom (Mitragyna speciosa): In vitro studies with implications for efficacy and drug interactions
por: Todd, D. A., et al.
Publicado: (2020) -
Clinical Assessment of the Drug Interaction Potential of the Psychotropic Natural Product Kratom
por: Tanna, Rakshit S., et al.
Publicado: (2023) -
Translating Kratom-Drug Interactions: From Bedside to Bench and Back
por: Tanna, Rakshit S., et al.
Publicado: (2023) -
Kratom (Mitragyna speciosa)-Induced Hepatitis
por: Allison, Devin R., et al.
Publicado: (2022)