Influence of Substitutions in the Binding Motif of Proline-Rich Antimicrobial Peptide ARV-1502 on 70S Ribosome Binding and Antimicrobial Activity

Proline-rich antimicrobial peptides (PrAMPs) are promising candidates to treat bacterial infections. The designer peptide ARV-1502 exhibits strong antimicrobial effects against Enterobacteriaceae both in vitro and in vivo. Since the inhibitory effects of ARV-1502 reported for the 70 kDa heat-shock p...

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Detalles Bibliográficos
Autores principales: Brakel, Alexandra, Krizsan, Andor, Itzenga, Renke, Kraus, Carl N., Otvos, Laszlo, Hoffmann, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8950706/
https://www.ncbi.nlm.nih.gov/pubmed/35328571
http://dx.doi.org/10.3390/ijms23063150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8950706/
https://www.ncbi.nlm.nih.gov/pubmed/35328571
http://dx.doi.org/10.3390/ijms23063150

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