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A Selective Inhibitor of Cardiac Troponin I Phosphorylation by Delta Protein Kinase C (δPKC) as a Treatment for Ischemia-Reperfusion Injury

Myocardial infarction is the leading cause of cardiovascular mortality, with myocardial injury occurring during ischemia and subsequent reperfusion (IR). We previously showed that the inhibition of protein kinase C delta (δPKC) with a pan-inhibitor (δV1-1) mitigates myocardial injury and improves mi...

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Detalles Bibliográficos
Autores principales: Qvit, Nir, Lin, Amanda J., Elezaby, Aly, Ostberg, Nicolai P., Campos, Juliane C., Ferreira, Julio C. B., Mochly-Rosen, Daria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8950820/
https://www.ncbi.nlm.nih.gov/pubmed/35337069
http://dx.doi.org/10.3390/ph15030271