Recombination Mediator Proteins: Misnomers That Are Key to Understanding the Genomic Instabilities in Cancer

Recombination mediator proteins have come into focus as promising targets for cancer therapy, with synthetic lethal approaches now clinically validated by the efficacy of PARP inhibitors in treating BRCA2 cancers and RECQ inhibitors in treating cancers with microsatellite instabilities. Thus, unders...

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Detalles Bibliográficos
Autores principales: Courcelle, Justin, Worley, Travis K., Courcelle, Charmain T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8950967/
https://www.ncbi.nlm.nih.gov/pubmed/35327990
http://dx.doi.org/10.3390/genes13030437

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8950967/
https://www.ncbi.nlm.nih.gov/pubmed/35327990
http://dx.doi.org/10.3390/genes13030437

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