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Recombination Mediator Proteins: Misnomers That Are Key to Understanding the Genomic Instabilities in Cancer
Recombination mediator proteins have come into focus as promising targets for cancer therapy, with synthetic lethal approaches now clinically validated by the efficacy of PARP inhibitors in treating BRCA2 cancers and RECQ inhibitors in treating cancers with microsatellite instabilities. Thus, unders...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8950967/ https://www.ncbi.nlm.nih.gov/pubmed/35327990 http://dx.doi.org/10.3390/genes13030437 |