Untargeted Metabolomics Showed Accumulation of One-Carbon Metabolites to Facilitate DNA Methylation during Extracellular Matrix Detachment of Cancer Cells

Tumor cells detached from the extracellular matrix (ECM) undergo anoikis resistance and metabolic reprogramming to facilitate cancer cell survival and promote metastasis. During ECM detachment, cancer cells utilize genomic methylation to regulate transcriptional events. One-carbon (1C) metabolism is...

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Detalles Bibliográficos
Autores principales: Nur, Suza Mohammad, Shait Mohammed, Mohammed Razeeth, Zamzami, Mazin A., Choudhry, Hani, Ahmad, Aamir, Ateeq, Bushra, Rather, Irfan A., Khan, Mohammad Imran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8951017/
https://www.ncbi.nlm.nih.gov/pubmed/35323710
http://dx.doi.org/10.3390/metabo12030267

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8951017/
https://www.ncbi.nlm.nih.gov/pubmed/35323710
http://dx.doi.org/10.3390/metabo12030267

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