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Pericentromeric Non-Coding DNA Transcription Is Associated with Niche Impairment in Patients with Ineffective or Partially Effective Multiple Myeloma Treatment

Mesenchymal stromal cells (MSC) ‘educated’ by tumor cells are an essential component of the multiple myeloma (MM) tumor microenvironment (TME) involved in tumor progression. Transcription of tandemly repeated (TR) non-coding DNA is often activated in many tumors and is required for tumor progression...

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Detalles Bibliográficos
Autores principales: Enukashvily, Natella I., Semenova, Natalia, Chubar, Anna V., Ostromyshenskii, Dmitry I., Gushcha, Ekaterina A., Gritsaev, Sergei, Bessmeltsev, Stanislav S., Rugal, Viktor I., Prikhodko, Egor M., Kostroma, Ivan, Zherniakova, Anastasia, Kotova, Anastasia V., Belik, Liubov A., Shumeev, Alexander, Maslennikova, Irina I., Ivolgin, Dmitry I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8951104/
https://www.ncbi.nlm.nih.gov/pubmed/35328779
http://dx.doi.org/10.3390/ijms23063359