Synthesis and Properties of α-Mangostin and Vadimezan Conjugates with Glucoheptoamidated and Biotinylated 3rd Generation Poly(amidoamine) Dendrimer, and Conjugation Effect on Their Anticancer and Anti-Nematode Activities

α-Mangostin and vadimezan are widely studied potential anticancer agents. Their biological activities may be improved by covalent bonding by amide or ester bonds with the third generation poly(amidoamine) (PAMAM) dendrimer, substituted with α-D-glucoheptono-1,4-lactone and biotin. Thus, conjugates o...

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Detalles Bibliográficos
Autores principales: Markowicz, Joanna, Wołowiec, Stanisław, Rode, Wojciech, Uram, Łukasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8951109/
https://www.ncbi.nlm.nih.gov/pubmed/35335982
http://dx.doi.org/10.3390/pharmaceutics14030606

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8951109/
https://www.ncbi.nlm.nih.gov/pubmed/35335982
http://dx.doi.org/10.3390/pharmaceutics14030606

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