Complex of HIV-1 Integrase with Cellular Ku Protein: Interaction Interface and Search for Inhibitors

The interaction of HIV-1 integrase and the cellular Ku70 protein is necessary for HIV replication due to its positive effect on post-integration DNA repair. We have previously described in detail the Ku70 binding site within integrase. However, the integrase binding site in Ku70 remained poorly char...

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Detalles Bibliográficos
Autores principales: Ilgova, Ekaterina, Galkin, Simon, Khrenova, Maria, Serebryakova, Marina, Gottikh, Marina, Anisenko, Andrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8951179/
https://www.ncbi.nlm.nih.gov/pubmed/35328329
http://dx.doi.org/10.3390/ijms23062908

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8951179/
https://www.ncbi.nlm.nih.gov/pubmed/35328329
http://dx.doi.org/10.3390/ijms23062908

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