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Complex of HIV-1 Integrase with Cellular Ku Protein: Interaction Interface and Search for Inhibitors
The interaction of HIV-1 integrase and the cellular Ku70 protein is necessary for HIV replication due to its positive effect on post-integration DNA repair. We have previously described in detail the Ku70 binding site within integrase. However, the integrase binding site in Ku70 remained poorly char...
Autores principales: | Ilgova, Ekaterina, Galkin, Simon, Khrenova, Maria, Serebryakova, Marina, Gottikh, Marina, Anisenko, Andrey |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8951179/ https://www.ncbi.nlm.nih.gov/pubmed/35328329 http://dx.doi.org/10.3390/ijms23062908 |
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