Apocynin-Tandospirone Derivatives Suppress Methamphetamine-Induced Hyperlocomotion in Rats with Neonatal Exposure to Dizocilpine

Accumulating evidence implicates oxidative stress as a potential pathophysiological mechanism of schizophrenia. Accordingly, we synthesized new chemicals using apocynin and tandospirone as lead compounds (A-2, A-3 and A-4). These novel compounds decreased reactive oxygen species (ROS) concentrations...

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Detalles Bibliográficos
Autores principales: Uehara, Takashi, Kurachi, Masayoshi, Kondo, Takashi, Abe, Hitoshi, Itoh, Hiroko, Sumiyoshi, Tomiki, Suzuki, Michio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8951253/
https://www.ncbi.nlm.nih.gov/pubmed/35330366
http://dx.doi.org/10.3390/jpm12030366

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8951253/
https://www.ncbi.nlm.nih.gov/pubmed/35330366
http://dx.doi.org/10.3390/jpm12030366

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