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Pleiotropic Effects of Common and Rare GCKR Exonic Mutations on Cardiometabolic Traits

Background: The common non-synonymous mutation of the glucokinase regulator (GCKR) gene, namely rs1260326, is widely reported to have pleiotropic effects on cardio-metabolic traits and hematological parameters. Objective: This study aimed to identify whether other GCKR variants may have pleiotropic...

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Detalles Bibliográficos
Autores principales: Yeh, Kuan-Hung, Hsu, Lung-An, Teng, Ming-Sheng, Wu, Semon, Chou, Hsin-Hua, Ko, Yu-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8951277/
https://www.ncbi.nlm.nih.gov/pubmed/35328045
http://dx.doi.org/10.3390/genes13030491