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Cleavage of LOXL1 by BMP1 and ADAMTS14 Proteases Suggests a Role for Proteolytic Processing in the Regulation of LOXL1 Function

Members of the lysyl oxidase (LOX) family catalyze the oxidative deamination of lysine and hydroxylysine residues in collagen and elastin in the initiation step of the formation of covalent cross-links, an essential process for connective tissue maturation. Proteolysis has emerged as an important le...

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Detalles Bibliográficos
Autores principales: Rosell-García, Tamara, Rivas-Muñoz, Sergio, Colige, Alain, Rodriguez-Pascual, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8951505/
https://www.ncbi.nlm.nih.gov/pubmed/35328709
http://dx.doi.org/10.3390/ijms23063285