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Supramolecular Complexes of Plant Neurotoxin Veratridine with Cyclodextrins and Their Antidote-like Effect on Neuro-2a Cell Viability

Veratridine (VTD) is a plant neurotoxin that acts by blocking the voltage-gated sodium channels (VGSC) of cell membranes. Symptoms of VTD intoxication include intense nausea, hypotension, arrhythmia, and loss of consciousness. The treatment for the intoxication is mainly focused on treating the symp...

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Detalles Bibliográficos
Autores principales: Uribe, Laura A., Leonardo, Sandra, Nielsen, Thorbjørn Terndrup, Steinmann, Casper, Campàs, Mònica, Fragoso, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8951692/
https://www.ncbi.nlm.nih.gov/pubmed/35335973
http://dx.doi.org/10.3390/pharmaceutics14030598