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Supramolecular Complexes of Plant Neurotoxin Veratridine with Cyclodextrins and Their Antidote-like Effect on Neuro-2a Cell Viability
Veratridine (VTD) is a plant neurotoxin that acts by blocking the voltage-gated sodium channels (VGSC) of cell membranes. Symptoms of VTD intoxication include intense nausea, hypotension, arrhythmia, and loss of consciousness. The treatment for the intoxication is mainly focused on treating the symp...
Autores principales: | Uribe, Laura A., Leonardo, Sandra, Nielsen, Thorbjørn Terndrup, Steinmann, Casper, Campàs, Mònica, Fragoso, Alex |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8951692/ https://www.ncbi.nlm.nih.gov/pubmed/35335973 http://dx.doi.org/10.3390/pharmaceutics14030598 |
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