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Alpha-Ketoglutarate Promotes Goblet Cell Differentiation and Alters Urea Cycle Metabolites in DSS-Induced Colitis Mice

The metabolite, alpha-ketoglutarate (aKG), shows promise as an approach for ameliorating colitis, but much remains unknown about the full extent of its effects on the metabolome and mucosal barrier. To further elucidate this matter, C57BL/6 male mice received drinking water with or without 1% aKG fo...

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Detalles Bibliográficos
Autores principales: Bravo Iniguez, Alejandro, Tian, Qiyu, Du, Min, Zhu, Mei-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8951758/
https://www.ncbi.nlm.nih.gov/pubmed/35334805
http://dx.doi.org/10.3390/nu14061148