Long-Lasting Exendin-4-Loaded PLGA Nanoparticles Ameliorate Cerebral Ischemia/Reperfusion Damage in Diabetic Rats

Exendin-4 (Ex-4) is an incretin mimetic agent approved for diabetes treatment and neuronal protection. However, the required frequent injections restrict its clinical application. We prepared Ex-4-loaded poly(d,l-lactide-co-glycolide) nanoparticles (PEx-4) and investigated their effect on cerebral i...

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Detalles Bibliográficos
Autores principales: Chung, Cheng-Hsun, Chung, Shiu-Dong, Cheng, Yu-Hsuan, Yang, Chun-Pai, Chien, Chiang-Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8951777/
https://www.ncbi.nlm.nih.gov/pubmed/35330390
http://dx.doi.org/10.3390/jpm12030390

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8951777/
https://www.ncbi.nlm.nih.gov/pubmed/35330390
http://dx.doi.org/10.3390/jpm12030390

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