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In Silico and In Vitro Identification of Pan-Coronaviral Main Protease Inhibitors from a Large Natural Product Library

The main protease (M(pro) or 3CL(pro)) in coronaviruses represents a promising specific drug target as it is essential for the cleavage of the virus polypeptide and has a unique cleavage site that does not exist in human host proteases. In this study, we explored potential natural pan-coronavirus dr...

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Detalles Bibliográficos
Autores principales:	Shahhamzehei, Nasim, Abdelfatah, Sara, Efferth, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8952009/ https://www.ncbi.nlm.nih.gov/pubmed/35337106 http://dx.doi.org/10.3390/ph15030308

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