Synthesis, Antiplasmodial, and Antileukemia Activity of Dihydroartemisinin–HDAC Inhibitor Hybrids as Multitarget Drugs

Artemisinin-based combination therapies (ACTs) are the gold standard for the treatment of malaria, but the efficacy is threatened by the development of parasite resistance. Histone deacetylase inhibitors (HDACis) are an emerging new class of potential antiplasmodial drugs. In this work, we present t...

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Detalles Bibliográficos
Autores principales: von Bredow, Lukas, Schäfer, Thomas Martin, Hogenkamp, Julian, Tretbar, Maik, Stopper, Daniel, Kraft, Fabian B., Schliehe-Diecks, Julian, Schöler, Andrea, Borkhardt, Arndt, Bhatia, Sanil, Held, Jana, Hansen, Finn K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8952208/
https://www.ncbi.nlm.nih.gov/pubmed/35337131
http://dx.doi.org/10.3390/ph15030333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8952208/
https://www.ncbi.nlm.nih.gov/pubmed/35337131
http://dx.doi.org/10.3390/ph15030333

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