Simple Zn-Mediated Seleno- and Thio-Functionalization of Steroids at C-1 Position

Here we report the reaction in the biphasic system of the in situ prepared selenols and thiols with 1,4-androstadiene-3,17-dione (1) or prednisone acetate (2) having α,β-unsaturated ketone as an electrophilic functionalization. The Michael-type addition reaction resulted to be chemo- and stereoselec...

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Detalles Bibliográficos
Autores principales: Grześ, Paweł A., Monti, Bonifacio, Wawrusiewicz-Kurylonek, Natalia, Bagnoli, Luana, Sancineto, Luca, Jastrzebska, Izabella, Santi, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8952209/
https://www.ncbi.nlm.nih.gov/pubmed/35328446
http://dx.doi.org/10.3390/ijms23063022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8952209/
https://www.ncbi.nlm.nih.gov/pubmed/35328446
http://dx.doi.org/10.3390/ijms23063022

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