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Enhancing the Antipsychotic Effect of Risperidone by Increasing Its Binding Affinity to Serotonin Receptor via Picric Acid: A Molecular Dynamics Simulation

The aim of this study was to assess the utility of inexpensive techniques in evaluating the interactions of risperidone (Ris) with different traditional π-acceptors, with subsequent application of the findings into a Ris pharmaceutical formulation with improved therapeutic properties. Molecular dock...

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Detalles Bibliográficos
Autores principales: Alhomrani, Majid, Alsanie, Walaa F., Alamri, Abdulhakeem S., Alyami, Hussain, Habeeballah, Hamza, Alkhatabi, Heba A., Felimban, Raed I., Haynes, John M., Shakya, Sonam, Raafat, Bassem M., Refat, Moamen S., Gaber, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8952232/
https://www.ncbi.nlm.nih.gov/pubmed/35337083
http://dx.doi.org/10.3390/ph15030285