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Enhancing the Antipsychotic Effect of Risperidone by Increasing Its Binding Affinity to Serotonin Receptor via Picric Acid: A Molecular Dynamics Simulation
The aim of this study was to assess the utility of inexpensive techniques in evaluating the interactions of risperidone (Ris) with different traditional π-acceptors, with subsequent application of the findings into a Ris pharmaceutical formulation with improved therapeutic properties. Molecular dock...
Autores principales: | Alhomrani, Majid, Alsanie, Walaa F., Alamri, Abdulhakeem S., Alyami, Hussain, Habeeballah, Hamza, Alkhatabi, Heba A., Felimban, Raed I., Haynes, John M., Shakya, Sonam, Raafat, Bassem M., Refat, Moamen S., Gaber, Ahmed |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8952232/ https://www.ncbi.nlm.nih.gov/pubmed/35337083 http://dx.doi.org/10.3390/ph15030285 |
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